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Welcome to the July 2009 Cell Migration Update, your one-stop resource for news, highlights and research on cell migration.

FEATURED ARTICLES

Specially written Editor's reviews of the hottest new articles

Breast cancer metastasis: A micro-cascade

miR-31 specifically prevents breast cancer metastatic invasion by inhibiting the expression of a cohort of metastasis-promoting genes.

Kim Baumann Original research paper: Cell 137, 1032-1046 (2009)

Centrosome orientation: Cell-cell contacts at PAR

The polarity protein PAR3 associates with dynein to regulate microtubule dynamics at cell–cell contacts and properly position the centrosome during directed migration.

Kim Baumann Original research paper: Current Biology, published online 18 June 2009.

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RESEARCH HIGHLIGHTS

Synopses of important recent articles

Breast cancer: Metastasis on the brain

A new study shows that breast cancer metastasis to the brain usually occurs after metastasis to other organs because cells must be capable of not only general extravasation but also of passing through the blood-brain barrier.

Sarah Seton-rogersNature Reviews Cancer 9, 460 - 461 (2009)

Coronin switches roles in actin disassembly depending on the nucleotide state of actin

It has been shown that whether coronin inhibits or promotes cofilin-mediated actin disassembly depends on the nucleotide state of actin.

Nature Reviews Molecular Cell Biology 10, 441 (2009)

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NEWS

The latest news selected from the CMC, Nature News and journals from the Nature family

Too few women in clinical trials?

Cancer-drug studies fail to reflect true incidence of disease in the population.


CELL MIGRATION KNOWLEDGEBASE

From Zamir & Geiger 2001; J. Cell Sc. 114:3583-90. Reproduced with permission from the Company of Biologists.

Visit the Cell Migration Knowledgebase for the latest cell migration protein database entries.

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CONSORTIUM ACTIVITIES

From Nalbant et al. 2004; Science 305:1615-19. Reprinted with permission from AAAS.

Find out more about the Consortium activities, and the latest Consortium Updates.