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Welcome to the May 2012 Cell Migration Update, your one-stop resource for news, highlights and research on cell migration.

CELL MIGRATION @ NATURE.COM

A comprehensive library of the latest research related to cell migration

Whacked and Rab35 polarize dynein-motor-complex-dependent seamless tube growth

Jodi Schottenfeld-Roames & Amin S. Ghabrial Nature Cell Biology

Lymphatic and interstitial flow in the tumour microenvironment: linking mechanobiology with immunity

Melody A. Swartz & Amanda W. Lund Nature Reviews Cancer

MTBP suppresses cell migration and filopodia formation by inhibiting ACTN4

N Agarwal, A S Adhikari, S V Iyer, K Hekmatdoost, D R Welch, T Iwakuma Oncogene

N-cadherin regulates mammary tumor cell migration through Akt3 suppression

S Chung, J Yao, K Suyama, S Bajaj, X Qian, O D Loudig, E A Eugenin, G R Phillips, R B Hazan Oncogene

Dimensional and temporal controls of three-dimensional cell migration by zyxin and binding partners

Stephanie I. Fraley, Yunfeng Feng, Anjil Giri, Gregory D. Longmore, Denis Wirtz Nature Communications

FEATURED ARTICLES

Editor's reviews of the hottest new articles

Cells need Arp2/3 to remain en route from A to B

A deficiency in ARPC3 reveals a requirement for the Arp2/3 complex in the generation of lamellipodia and in fibroblast persistent directional migration.

Katrin Legg Original research paper: J. Cell Biol. 197, 239-251 (2012)


CELL MIGRATION KNOWLEDGEBASE

From Zamir & Geiger 2001; J. Cell Sc. 114:3583-90. Reproduced with permission from the Company of Biologists.

Visit the Cell Migration Knowledgebase for the latest cell migration protein database entries.

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CONSORTIUM ACTIVITIES

From Nalbant et al. 2004; Science 305:1615-19. Reprinted with permission from AAAS.

Find out more about the Consortium activities, and the latest Consortium Updates.

RESEARCH HIGHLIGHTS

Synopses of important recent articles

Ovarian cancer: Driving force

Actomyosin-mediated contractility in ovarian cancer cells induces mesothelial cells to de-adhere and move away, facilitating penetration of the mesothelial barrier during metastasis.

Sarah Seton-RogersNature Reviews Cancer 11, 538 - 539 (2011)

Innate immunity: Neutrophil U-turn fans the flames

The expression of junctional adhesion molecule C in endothelial cells is required to prevent reverse transendothelial migration of neutrophils.

Yvonne BordonNature Reviews Immunology 11, 498 (2011)

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